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Prostatitis Center

Tucson, Arizona

The role of Corynebacteria

J. Polacheck, D. Michaud, E Vega
Prostatitis Center and Carondelet Hospitals, Tucson, AZ
We wish to present preliminary results from an ongoing study about the role of corynebacteria (diptheroids) in patients who present with clinical signs and symptoms of chronic prostatitis.
  1. We have isolated corynebacteria (diptheroids) from about 25 percent of EPS specimens from patients with "chronic prostatitis" using a combination of three different agar plates: sheep blood, tellurite, and horse serum agar. Cornybacteria did not grow consistently on any one of the three media.

  2. Most of these patients had prominent urethral symptoms suggesting chronic prostatic urethritis (CPU).

  3. Not infrequently, bipolar short gram positive rods were observed, cytologically, in association with reactive squamoid cells in the EPS from these patients.

  4. Antibiotic sensitivity tests were performed utilizing the Kirby-Bauer method (discs). No consistent sensitivity pattern was observed.

  5. Although this sensitivity testing method has not been standardized for cornybacteria, most patients improved clinically when they were treated with the antibiotics suggested to be effective by these tests.

  6. Studies to identify the corynebacteria are in progress. It appears that several different species play a role in CPU.
Therefore, we believe that corynebacteria do play a major role in patients with "chronic prostatitis," especially those with CPU.
Return to 1999 NIH abstracts

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